May is all about mothers and women’s hormones. A woman’s overall health is affected by hormonal balances that change throughout different phases like menarche, postpartum, and menopause. The two main hormones in women are estrogen and progesterone. These two hormones are necessary for female sexual characteristics and female reproductive health. Balanced hormones promote healthy menstruation, pregnancy, and lactation, while also supporting cardiovascular, bone, urinary, digestive, cognitive, and immune health.

When these hormones are unbalanced, they can lead to dysfunction in the body and mind. Certain conditions that are a result of hormonal imbalance include perturbations in androgen activity, estrogen metabolism, and hormone detoxification/elimination. These imbalances can lead to multiple impaired functions such as estrogen dominance, polycystic ovary syndrome (PCOS), hirsutism, androgen excess, PMS, dysmenorrhea, and infertility. Inflammation, exogenous stressors, and oxidative stress are linked to hormonal imbalances. This clinical protocol is designed to specifically support female hormone balance and activity through lifestyle adaptations, healthy balanced diets, and nutrient-rich supplements.

A recommended way to start balancing hormones is by having a hormone test taken. An estrogen metabolite/estrogen ratio test should be considered to monitor levels for hypoglycemia, hypothyroidism, adrenal insufficiency, insulin levels, HbA1c, liver function, GSH, and zinc status. We offer these tests in our office. A balanced diet is also recommended for hormone balance support. This diet includes:

  • High intake of cruciferous vegetables for consumption of isothiocyanates. These foods include Bok Choy, broccoli, Brussels sprouts, cabbage, cauliflower, kale, etc.
  • Adequate intake of fiber to support stable blood sugar metabolism and elimination of hormone metabolites (25 to 30 g/day).
  • Antioxidant-rich whole foods like dark chocolate, pecans, strawberries, artichokes, blueberries, raspberries, beets, spinach, avocados, etc.
  • Adequate zinc intake through rich sources like oysters, liver, beef, pork, crab, lobster, baked beans, and egg yolks (8 mg/day; 11 mg/day during pregnancy; 12 mg/day during lactation).
  • Moderating alcohol and caffeine intake.

The last piece of the hormone protocol is the nutrient-rich supplements. These supplements promote healthy hormone balance. These supplements include:

  • DIM – Evail (1-2 capsules/day) uses a blend of diindolylmethane, MCT, quillaja extract, and tocotrienols to support healthy estrogen and metabolism. One tablet a day will keep your estrogen healthy as well as your metabolism.
  • FemGuard + Balance (4 capsules/day) promotes hormonal balance, antioxidant status, and hormone detoxification by using a blend of vital nutrients and herbs (vitex, polygonum, black cohosh, DIM).
  • Pregnenolone CRT (1 capsule/day) supports healthy cognitive function, memory, and hormone balance. By using controlled-release technology, Pregnenolone CRT copies the way that Pregnenolone is naturally released into the body stimulating healthy cognitive function, memory, and hormone balance.
  • Progest – Avail (1 milliliter/day) is a serum that provides progesterone that will aid in healthy menstruation, aging, and hormonal balance.
  • FemGuard – HF (2 capsules/day) is specifically designed to help decrease the number of hot flashes during menopause.
  • BroccoProtect (1 capsule/day) supports detoxification pathways, antioxidant status, healthy estrogen metabolism, and cellular health. 
  • Zinc Supreme (1 capsule/day) offers chelated minerals by using a 2:1 ratio of amino acid glycine and zinc for optimal absorption.

These supplements will help keep hormones balanced. You can view this supplement protocol on Fullscript!

Keeping hormones balanced is very important, so we hope you will take some of these recommendations to keep your hormones balanced and in check!

References:

1. Fuhrman BJ, Schairer C, Gail MH, et al. Estrogen metabolism and risk of breast cancer in postmenopausal women. JNCI J Natl Cancer Inst. 2012;104(4):326‑339. doi:10.1093/jnci/djr531 

2. Delgado BJ, Lopez‑Ojeda W. Estrogen. In: StatPearls. StatPearls Publishing; 2023. Accessed June 8, 2023. http://www.ncbi.nlm.nih.gov/books/NBK538260/ 

3. Cable JK, Grider MH. Physiology, progesterone. In: StatPearls. StatPearls Publishing; 2023. Accessed June 8, 2023. http://www.ncbi.nlm.nih.gov/books/NBK558960/ 

4. Dietz BM, Hajirahimkhan A, Dunlap TL, Bolton JL. Botanicals and their bioactive phytochemicals for women’s health. Pharmacol Rev. 2016;68(4):1026‑1073. doi:10.1124/pr.115.010843 

5. Baker JM, Al‑Nakkash L, Herbst‑Kralovetz MM. Estrogen‑gut microbiome axis: physiological and clinical implications. Maturitas. 2017;103:45‑53. doi:10.1016/j.maturitas.2017.06.025 

6. Jamilian M, Foroozanfard F, Bahmani F, Talaee R, Monavari M, Asemi Z. Effects of zinc supplementation on endocrine outcomes in women with polycystic ovary syndrome: a randomized, double‑blind, placebo‑controlled trial. Biol Trace Elem Res. 2016;170(2):271‑278. doi:10.1007/s12011‑015‑0480‑7 

7. Nasiadek M, Stragierowicz J, Klimczak M, Kilanowicz A. The role of zinc in selected female reproductive system disorders. Nutrients. 2020;12(8):2464. doi:10.3390/nu12082464 

8. Lei R, Sun Y, Liao J, et al. Sex hormone levels in females of different ages suffering from depression. BMC Womens Health. 2021;21:215. doi:10.1186/s12905‑021‑01350‑0

9. Mumford SL, Browne RW, Schliep KC, et al. Serum antioxidants are associated with serum reproductive hormones and ovulation among healthy women. J Nutr. 2016;146(1):98‑106. doi:10.3945/jn.115.217620 

10. Morales‑Prieto DM, Herrmann J, Osterwald H, et al. Comparison of dienogest effects upon 3,3’–diindolylmethane supplementation in models of endometriosis and clinical cases. Reprod Biol. 2018;18(3):252‑258. doi:10.1016/j.repbio.2018.07.002 

11. Fowke JH, Longcope C, Hebert JR. Brassica vegetable consumption shifts estrogen metabolism in healthy postmenopausal women. Cancer Epidemiol Biomark Prev Publ Am Assoc Cancer Res Cosponsored Am Soc Prev Oncol. 2000;9(8):773‑779. 

12. Jiang Y, Wu SH, Shu XO, et al. Cruciferous vegetable intake is inversely correlated with circulating levels of proinflammatory markers in women. J Acad Nutr Diet. 2014;114(5):700‑8.e2. doi:10.1016/j.jand.2013.12.019 

13. Reynolds AN, Akerman AP, Mann J. Dietary fibre and whole grains in diabetes management: systematic review and meta‑analyses. PLoS Med. 2020;17(3):e1003053. doi:10.1371/journal.pmed.1003053 

14. Gaskins AJ, Mumford SL, Zhang C, et al. Effect of daily fiber intake on reproductive function: the BioCycle Study123. Am J Clin Nutr. 2009;90(4):1061‑1069. doi:10.3945/ajcn.2009.27990 

15. Zengul AG, Demark‑Wahnefried W, Barnes S, et al. Associations between dietary fiber, the fecal microbiota and estrogen metabolism in postmenopausal women with breast cancer. Nutr Cancer. 2021;73(7):1108‑1117. doi:10.1080/01635581.2020.1784444 

16. Saadati N, Haidari F, Barati M, Nikbakht R, Mirmomeni G, Rahim F. The effect of low glycemic index diet on the reproductive and clinical profile in women with polycystic ovarian syndrome: a systematic review and meta‑analysis. Heliyon. 2021;7(11):e08338. doi:10.1016/j.heliyon.2021.e08338 

17. Sauer AK, Hagmeyer S, Grabrucker AM, Sauer AK, Hagmeyer S, Grabrucker AM. Zinc deficiency. In: Nutritional Deficiency. IntechOpen; 2016. doi:10.5772/63203 

18. Mazaheri Nia L, Iravani M, Abedi P, Cheraghian B. Effect of zinc on testosterone levels and sexual function of postmenopausal women: a randomized controlled trial. J Sex Marital Ther. 2021;47(8):804‑813. doi:10.1080/0092623X.2021.1957732 

19. Schliep KC, Zarek SM, Schisterman EF, et al. Alcohol intake, reproductive hormones, and menstrual cycle function: a prospective cohort study. Am J Clin Nutr. 2015;102(4):933‑942. doi:10.3945/ajcn.114.102160 

20.Schliep KC, Schisterman EF, Mumford SL, et al. Caffeinated beverage intake and reproductive hormones among premenopausal women in the BioCycle Study123. Am J Clin Nutr. 2012;95(2):488‑497. doi:10.3945/ajcn.111.021287 

21. Ennour‑Idrissi K, Maunsell E, Diorio C. Effect of physical activity on sex hormones in women: a systematic review and meta‑analysis of randomized controlled trials. Breast Cancer Res BCR. 2015;17:139. doi:10.1186/s13058‑015‑0647‑3 

22.Im JY, Bang HS, Seo DY. The effects of 12 weeks of a combined exercise program on physical function and hormonal status in elderly Korean women. Int J Environ Res Public Health. 2019;16(21):4196. doi:10.3390/ijerph16214196 

23.Razzak ZA, Khan AA, Farooqui SI. Effect of aerobic and anaerobic exercise on estrogen level, fat mass, and muscle mass among postmenopausal osteoporotic females. Int J Health Sci. 2019;13(4):10‑16. 

24. Shele G, Genkil J, Speelman D. A Systematic review of the effects of exercise on hormones in women with polycystic ovary syndrome. J Funct Morphol Kinesiol. 2020;5(2):35. doi:10.3390/jfmk5020035 

25. Paterni I, Granchi C, Minutolo F. Risks and benefits related to alimentary exposure to xenoestrogens. Crit Rev Food Sci Nutr. 2017;57(16):3384‑3404. doi:10.1080/10408398.2015.1126547

26.Wang LH, Chen LR, Chen KH. In vitro and vivo identification, metabolism and action of xenoestrogens: an overview. Int J Mol Sci. 2021;22(8):4013. doi:10.3390/ijms22084013

Locations

Office Hours

CALL or TEXT for an appointment (843) 236-9810

Dr. Tori Ritchie, DC and Dr. Sandra Buffkin, DC

Monday

9:00 am - 1:00 pm

Tuesday

1:00 pm - 6:00 pm

Wednesday

9:00 am - 1:00 pm

3:00 pm - 4:00 pm

Thursday

9:00 am - 1:00 pm

2:00 pm - 6:00 pm

Friday

9:00 am - 1:00 pm

Saturday

Closed

Sunday

Closed

Dr. Tori Ritchie, DC and Dr. Sandra Buffkin, DC

Monday
9:00 am - 1:00 pm
Tuesday
1:00 pm - 6:00 pm
Wednesday
9:00 am - 1:00 pm 3:00 pm - 4:00 pm
Thursday
9:00 am - 1:00 pm 2:00 pm - 6:00 pm
Friday
9:00 am - 1:00 pm
Saturday
Closed
Sunday
Closed